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Opioid Dependence Found to Permanently Change Brains of Rats

UC San Diego Health — January 24, 2020

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, UC San Diego researchers found that opioid dependence produced permanent changes in the brains of rats.

Liver Fibrosis 'Off Switch' Discovered in Mice

UC San Diego Health — January 23, 2020

UC San Diego School of Medicine researchers identified several genetic switches, or transcription factors, that determine whether or not liver cells produce collagen — providing a new therapeutic target for liver fibrosis.

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