Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, UC San Diego researchers found that opioid dependence produced permanent changes in the brains of rats.
UC San Diego School of Medicine researchers identified several genetic switches, or transcription factors, that determine whether or not liver cells produce collagen — providing a new therapeutic target for liver fibrosis.
Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink…
Researchers say a gene known to be a biomarker of age plays a key role in age-associated functional and anatomical aging in mouse retinas, a finding that has direct relevance to age-related eye diseases.
Using novel imaging technologies, researchers produce first whole-brain atlas at single-cell resolution, revealing how alcohol addiction and abstinence remodel neural physiology and function in mice.
University of California San Diego School of Medicine researchers report that patients with prostate cancer assigned to eat seven or more servings of vegetables and fruits daily saw no extra protection from the increased consumption of micronutrients, running contrary to current thought.
University of California San Diego School of Medicine researchers identified how THC from marijuana accelerates cancer growth in patients with human papillomavirus (HPV)-positive head and neck cancer.
UC San Diego School of Medicine researchers have discovered how a new immune system works to protect bacteria from phages, viruses that infect bacteria — new information that could be leveraged to improve treatment of multidrug-resistant bacterial infections by refining phage therapy.
Researchers at University of California San Diego School of Medicine found the main characteristics of loneliness in a senior housing community and the strategies residents use to overcome it.
UC San Diego researchers studied nearly 900 vertebrate species and found that bats have unusual gut microbiomes that more closely resemble those of birds than other mammals, raising questions about how evolutionary pressures change the gut microbiome.
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