News From Around the System

Novel Coronavirus Circulated Undetected Months before First COVID-19 Cases in Wuhan, China

Study dates emergence to as early as October 2019; simulations suggest in most cases zoonotic viruses die out naturally before causing a pandemic

Therapy Sneaks into Hard Layer of Pancreatic Cancer Tumor and Destroys it From Within

In animal models, tumor-penetrating therapy allows chemotherapy drugs to be delivered deeper inside tumor tissue, increasing effectiveness

How Does Your Brain Process Emotions? Answer Could Help Address Loneliness Epidemic

Study finds specific brain regions respond opposingly to emotions related to loneliness and wisdom

Sewage-Handling Robots Help Predict COVID-19 Outbreaks in San Diego

Automated process helps test city sewage for SARS-CoV-2, allowing researchers to forecast the region’s caseload one to two weeks ahead of clinical diagnostic reports

Heart Disease is in the Eye of the Beholder

UC San Diego Health researchers see a possible way to detect heart disease through the eye

Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer’s Disease

In animal models, the new compound modulated a key enzyme, reducing or eliminating production of problematic protein fragments; human clinical trials needed

Repurposed Arthritis Drug Did Not Significantly Improve Severe COVID-19 Pneumonia

But researchers say tocilizumab, a monoclonal antibody treatment, may reduce ventilator use and shorten hospital stays

NIH Awards UC San Diego $33 Million for Five COVID-19 Diagnostic Projects

Efforts range from managing a large data center to expanding testing in disadvantaged communities

Human Lung and Brain Organoids Respond Differently to SARS-CoV-2 Infection in Lab Tests

Findings may help explain the wide variety in COVID-19 symptoms and aid search for therapies

Genetic Tool Improves Estimation of Prostate Cancer Risk in Diverse Ethnic/Racial Groups