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News From Around the System

Receptor location matters for psychedelic drug effects

UC Davis Health — February 16, 2023

Engaging specific serotonin receptors inside neurons promotes the growth of new connections, according to a new study. The findings will help guide efforts to discover new drugs for depression, PTSD and other disorders.

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Small Molecule Drug Reverses ADAR1-induced Cancer Stem Cell Cloning Capacity

UC San Diego Health — February 16, 2023

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1...

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