In a new study of older adults living in a senior continuing care facility, researchers at University of California San Diego School of Medicine parse how distinctive factors, such as wisdom, loneliness, income and sleep quality, impact the physical and mental functioning of older persons.
UC San Diego researchers linked a gut bacteria toxin to worse clinical outcomes in patients with alcoholic liver disease, and discovered that treatment with bacteriophages clears the bacteria and eliminates the disease in mice.
University of California San Diego School of Medicine researchers found that treating patients with personalized precision medicine that combined therapies to target multiple alterations improved outcomes in patients with therapy resistant cancers.
Researchers at UC San Diego say they are getting closer to identifying the mechanisms of autism spectrum disorder, revealing a critical gene network that is disrupted and which helps predict severity of symptoms.
Using stem cells derived from six people, UC San Diego School of Medicine researchers recapitulated retinal cells in the lab. This “eye-in-a-dish” model allowed them to identify genetic variants that cause age-related macular degeneration, a common cause of vision loss.
UC San Diego researchers report that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.
UC San Diego Health researchers surveyed and compared early- and late-stage breast and colorectal cancer diagnoses in patients in pre-pandemic 2019 and in 2020, the first full year of the COVID-19 pandemic, discovering fewer of the former and more of the latter as patients delayed care.
Researchers report that accumulating amyloid protein occurred faster among persons deemed to have "objectively-defined subtle cognitive difficulties" (Obj-SCD) than among persons considered to be "cognitively normal," offering a potential new early biomarker for Alzheimer's disease.
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