Researchers at UC San Diego School of Medicine found in a mouse model that when fed a Western diet rich in calories, fat and cholesterol, the mice progressively became obese, diabetic and developed NASH, which progressed to HCC, chronic kidney and cardiovascular disease.
Bernard Thurman was referred to a personalized cancer therapy trial at Moores Cancer Center at UC San Diego Health, a collaboration with the La Jolla Institute for Immunology, the trial employs a patient’s immune cells — specifically tumor infiltrating lymphocytes (TIL) — to destroy cancer cells.
Researchers at University of California San Diego School of Medicine are recruiting eligible children between the ages of seven and fourteen years for a Phase III clinical trial to determine whether cannabidiol (CBD) reduces severe behavior problems in children with autism spectrum disorder.
UC San Diego researchers discovered that the SARS-CoV-2 virus can’t grab hold of cell receptor ACE2 without a carbohydrate called heparan sulfate, which is also found on lung cell surfaces — disrupting that interaction with a repurposed drug may help treat COVID-19.
In an effort to help schools reduce the risk of COVID-19 outbreaks as they resume in-person instruction, UC San Diego and the County of San Diego are testing the Safer at School Early Alert system to detect SARS-CoV-2 at schools and child care centers.
A coalition of six U.S. subsidiary companies have sponsored a COVID-19 mobile clinic to vaccinate 10,000 maquiladora workers employed in Baja California, Mexico. UC San Diego Health is vaccinating about 1,500 workers daily.
UC San Diego researchers report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer’s disease.
Mining a large database of adverse reactions to medications, UC San Diego researchers found that people who took proton pump inhibitors (e.g., Prilosec, Nexium) for heartburn and acid reflux were more likely to experience kidney disease than people who took other forms of antacid.
UC San Diego researchers report that medications commonly prescribed to reduce the severity of physical and mental health symptoms associated with schizophrenia may have a cumulative effect of worsening cognitive function in patients.
Researchers identify molecular mechanism for the anti-inflammatory activity of diabetes drug metformin and, in mouse studies, say it prevents lung inflammation in animals infected with SARS-CoV-2, the virus that causes COVID-19.
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