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News From Around the System

Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes

UC San Diego Health — May 12, 2022

The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.

A New Way to Target Cancers Using 'Synthetic Lethality'

UC San Diego Health — May 12, 2022

Researchers at Ludwig Institute for Cancer Research and University of California San Diego School of Medicine report that inhibiting a key enzyme caused human cancer cells associated with two major types of breast and ovarian cancer to die and in mouse studies reduced tumor growth.

3D Printed Implant Promotes Nerve Cell Growth to Treat Spinal Cord Injury

UC San Diego Health — May 12, 2022

For the first time, researchers at University of California San Diego have used rapid 3D printing technologies to create a spinal cord, then successfully implanted that scaffolding, loaded with neural stem cells, into sites of severe spinal cord injury in rats.

$55M NIH Grant Advances Clinical and Translational Research at UC San Diego

UC San Diego Health — May 12, 2022

The Altman Clinical and Translational Research Institute at University of California San Diego has received a five-year, $54.7 million Clinical and Translational Science Award from the National Center for Advancing Translational Science (NCATS), part of the National Institutes of Health.

3D 'Assembloid' Shows How SARS-CoV-2 Infects Brain Cells

UC San Diego Health — May 12, 2022

Researchers at UC San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have produced a stem cell model that demonstrates a potential route of entry of SARS-CoV-2, the virus that causes COVID-19, into the human brain.

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