UCLA partners with Cal State Northridge to nurture students’ interest in science careers.

Sarah Imam, a Cal State Northridge student, is working in the stem cell research lab of Michael Teitell at UCLA .
Sarah Imam had her sights set on medical school until a unique program offered at Cal State University Northridge (CSUN) in partnership with the UCLA stem cell center steered her in a new direction.
A postdoctoral student at CSUN, Imam now envisions a future in science and medicine — with both a doctorate and medical degree — after spending time as a researcher in a laboratory at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.
Formed two years ago, the six-year partnership between UCLA and CSUN aims to offer a total of 10 CSUN students an eye-opening, mind-expanding opportunity to work in stem cell research labs under the mentorship of renowned stem cell scientists.
The CSUN-UCLA Bridges to Stem Cell Research program that helped realign her career goals is funded through the California Institute of Regenerative Medicine (CIRM), the state’s stem cell agency. By funding courses and research internships for undergraduates and masters-level students, CIRM seeks to train the next generation of stem cell scientists and laboratory technicians.
“It’s been amazing,” said Imam, 29, of North Hollywood. “I pinch myself every day that I get to go to UCLA and work in a lab. It’s a total immersion experience, which makes everything much easier to absorb.”
The Bridges students work full time in the labs and receive a monthly stipend of $2,500. The lab hosting the student receives $3,000 from CIRM, an amount matched by the UCLA Broad stem cell center, to pay for necessary research materials such as reagents, enzymes and other lab supplies. Bridges students also receive $2,000 to support their attendance at important stem cell conferences.
The stipend allows students to focus all of their attention on stem cell research. Participants are not allowed to hold other jobs, said Dr. Michael Teitell, a UCLA professor of pathology and laboratory medicine and pediatrics, a practicing physician and scientist who mentors Bridges students as well as helps coordinate the UCLA arm of the program.
“The goal is to train undergrads and master’s level students in stem cell biology,” said Teitell, who mentors Imam. “This provides an opportunity for students attending CSUN to work in top UCLA labs and get world-class exposure to stem cell science.”
Cindy Malone, an associate professor of biology at ULA, directs the program for CSUN. She characterizes Bridges as an “opportunity of a lifetime.
“The Bridges students are exposed to projects and experiences that we can’t provide to them here under any circumstances,” said Malone, who teaches and runs a lab at CSUN. “We don’t have the kind of research facilities or the resources that UCLA has. This program offers students the whole environment of being immersed in a research career.”
Students spend nine months to a year working in the UCLA stem cell labs. Once at UCLA, they’re paired with either a graduate or postdoctoral student who, with the guidance of the faculty mentor, helps them create and develop their own research project.
“It’s an intense commitment, and most of the students end up working a lot more than they thought they would,” Malone said. “The projects take on lives of their own and become all-consuming.”
That has proven true for Imam, who is studying the unique metabolic properties of stem cells, which are different than those of mature cells. She has found that the stem cell metabolism is very similar to cancer cell metabolism, and the conclusions she ultimately draws from her research may have implications for cancer research. She hopes to uncover an “Achilles heel” in cell metabolism that might one day prove to be a target for therapy.
“My experience in the Bridges program has changed my perspective,” she said. “I see research now as an indispensable element to medicine, and it’s exciting to think of a future contributing to solutions to challenging medical conditions.”
Immersed in the program, Imam attends weekly seminars that feature well-known scientists from other stem cell centers nationwide. She has also attended extramural symposia, where she has presented posters detailing her research project. In June, she’ll be traveling to Japan for the International Society of Stem Cell Research meeting, which draws top scientists from all over the world. She is hoping that an abstract of her research will be accepted.
Generally, Imam works seven days a week in Teitell’s lab, and her hours are flexible, planned around the experiments she needs to conduct for her research. Working long days is not unusual, she said.
“My experience has been consuming and an absolute pleasure,” Imam said. “I can’t believe a program like this really exists.”
Roonalika Wisidagama, 28, of Northridge, was in the first group of Bridges students to work in a UCLA stem cell laboratory. She worked as an undergraduate in Malone’s lab at CSUN and served as the lab manager. She recently was accepted in the doctoral program at the University of Utah and is currently completing her master’s thesis.
“It was definitely a very positive experience, very intense and I enjoyed every bit of it,” said Wisidagama, who has always wanted to be a scientist. “The Bridges program encouraged me, supported my goal to become a scientist and made me want to pursue master’s and doctorate degrees.”
She had been thinking about applying for positions in the biotech industry, but now may set her sights on a career at an academic medical center like UCLA because she found the experience so enriching.
Wisidagama, who also worked in Teitell’s lab, said she found her mentor to be very approachable and available.
“He’s incredibly busy, but his door is always open to you,” she said. “He knows how to talk science on multiple levels. I was an undergraduate when I went into his lab, and he knew not to overwhelm me at first. He was very good at giving me personal attention.”
Bridges officials currently are screening applicants to select the third round of students, who will start the program in the fall. In all, CIRM has given out 16 Bridges to Stem Cell Research Awards to state universities and community colleges across California.
And the program has succeeded in expanding UCLA’s workforce. Several program graduates are currently working in UCLA stem cell labs, Teitell said. Others have gone on to graduate school, medical school or applied for jobs in the biotech industry.
In addition to Teitell, UCLA stem cell scientists currently participating in the program include Dr. Owen Witte, the stem cell center director; Bennett Novitch; William Lowry; Dr. Hanna Mikkola; April Pyle; Jerry Zack; Dr. Brigitte Gomperts; Karen Lyons; and Dong Song An.













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